CVE-2026-31965CWE-125CWE-129

HTSlib CRAM reader has out-of-bounds reads due to improper validation of input

Medium · published March 18, 2026

CVSS v4.0
6.9
EPSS
0%
Percentile
39.7
In the wild
Unconfirmed
What it is

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the `cram_decode_slice()` function called while reading CRAM records, validation of the reference id field occurred too late, allowing two out of bounds reads to occur before the invalid data was detected. The bug does allow two values to be leaked to the caller, however as the function reports an error it may be difficult to exploit them. It is also possible that the program will crash due to trying to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

The record
Technical detail
CVSS v4.0
6.9 · MEDIUM
Vector
CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:L/VI:N/VA:L/SC:N/SI:N/SA:N
EPSS
0.00470 · 39.7th percentile
Weaknesses
CWE-125 · Out-of-bounds Read; CWE-129 · Improper Validation of Array Index
Published
2026-03-18T18:50Z
EPSS history
Timeline
  • 18 MAR 18:50Z
    HTSlib CRAM reader has out-of-bounds reads due to improper validation of input
    cvelistv5